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Stem Cell Therapy and Regenerative Medicine

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Solutions for Stem Cell Therapy Research

 

From measuring stem cell pluripotency to deep molecular characterization of pluripotent stem cells, assessing cell culture conditions and exploring organoid tissue function, together we can advance the field of regenerative medicine and improve the human condition.

Publications

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Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection.

We have shown that calcium-activated potassium (KCa)-channels regulate fundamental progenitor-cell functions, including proliferation, but their contribution to cell-therapy effectiveness is unknown. Here, we test the participation of KCa-channels in human heart explant-derived cell (EDC) physiology and therapeutic potential.

Translational investigation of electrophysiology in hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) patients are at increased risk of ventricular arrhythmias and sudden cardiac death, which can occur even in the absence of structural changes of the heart. HCM mouse models suggest mutations in myofilament components to affect Ca2+ homeostasis and thereby favor arrhythmia development.

Reactivation of a developmentally silenced embryonic globin gene.

The α- and β-globin loci harbor developmentally expressed genes, which are silenced throughout post-natal life. Reactivation of these genes may offer therapeutic approaches for the hemoglobinopathies, the most common single gene disorders.

Spotlight on Regenerative Medicine

Webinar A Brief nCounter virtual experience with the Stem Cell Characterization Panel
Webinar Call Stem Like You See Them. Enhancing Stem Cell Research with the NEW nCounter® Stem Cell Characterization Panel
Blog Pluripotent Stem Cells: How to Best Use Them in Your Research
Blog What is Regenerative Medicine?

Related Resources

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Product Bulletin nCounter® Stem Cell Characterization Panel Product Bulletin
Product Bulletin Glial Panel – Product Bulletin
Product Bulletin Metabolic Pathways Panel – Product Bulletin
Product Bulletin GeoMx Human Whole Transcriptome Atlas – Product Bulletin
Product Bulletin nCounter Neuropathology Panel – Product Bulletin
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