nCounter® Vantage 3D™ SNV Solid Tumor Panel

Designed to identify the most meaningful variants across a variety of solid tumor types, this panel includes somatic variants (SNVs, DNVs, and small InDels) associated with lung adenocarcinoma, thyroid carcinoma, pancreatic adenocarcinoma, colorectal adenocarcinoma, and melanoma. The genes and mutations covered are relevant to new and existing clinical trials, drug pipelines, tumor subtypes, drug resistance, and response.

  • 97 driver mutations from 24 key solid tumor genes
  • Only 5 ng DNA input requirement from FFPE, fresh/frozen, and cells
  • Sensitivity and Specificity above 95% on solid tumor samples with >5% allele frequency*
  • Concordance with gold standard mutational analysis techniques
  • Simultaneous multi-analyte profiling with Vantage 3D RNA and Protein Assays

*Validated on internal reference materials. Data may vary with the various quality of FFPE samples.


Curated Content

Feature Specifications
Solid Tumor Coverage Examples Examples such as lung adenocarcinoma, thyroid carcinoma, pancreatic adenocarcinoma, colorectal adenocarcinoma, and melanoma
Recommended amount of starting material 5 ng total genomic DNA
Sample types supported Human genomic DNA from FFPE samples, fresh or frozen tissue, or cell lines
Sensitivity and Specificity > 95%*
Number of SNVs detected 104 driver mutations + 20 controls
Time to Results < 24 hours
nCounter® Digital Analyzer throughput 12 samples/2.7 hours
Data Analysis nSolver™ Analysis 4.0 (Research use only)

*Might vary by FFPE quality

Product Description Catalog Number Unit Size
nCounter® Vantage 3D DNA SNV Solid Tumor Panel (CSO) Contains code set for 104 solid tumor actionable mutation over 25 genes. Includes Pre-Amplification Reagents. To be used as a stand-alone DNA assay or with nCounter Vantage 3D Protein and RNA. No Master Kit VDXC-HST-12 12 Reactions
nCounter® Vantage 3D SNV Qualification Kit (CSO) Contains synthetic oligos to qualify nCounter instruments before testing SNV Panel. To be used only one time for first time SNV users. No Master Kit. VDXC-QualK-12 12 Reactions

For Research Use Only. Not for use in diagnostic procedures.