nCounter® SPRINT Profiler

The introduction of the nCounter® SPRINT Profiler makes access to NanoString’s molecular barcode technology more affordable than ever before. Digitally examine multiple pathways in a single tube in an extraction-free workflow requiring only 10 minutes of hands-on time. Accelerate your research by spending less time on sample prep and perform your own data analysis using the included nSolver™ Analysis Software. Work with difficult sample types, including FFPE tissue. Learn how the new nCounter® SPRINT Profiler can benefit your RNA, DNA, and protein profiling applications. Highly multiplexed analysis of basic cancer biology and pathway deregulation activity

  • Maximize Sample: Don’t let samples limit your experimental design. Analyze 10s to 100s of targets simultaneously using single-tube multiplexing and avoid waste by eliminating RNA extraction; process crude cell lysates from as few as 2,500 cells.
  • Boost Productivity: Enjoy an intuitive workflow that requires only ten minutes of hands-on time from sample to data. Deploy this technology without the need to hire additional staff and free your team to advance other parts of your research project.
  • Simplify Data: Don’t waste time waiting for a bioinformatics specialist to review your data. Get results in a simple CSV file that contains direct counts for each target. Import it into your favorite application or use the included nSolver Analysis Software for convenient data analysis.
  • Detect Small Fold Changes: Eliminate cDNA synthesis, amplification, and library prep so you experience less technical variation in your assay. Generate high quality data from less sample input while simplifying your workflow by eliminating the need for experimental replicates.


Feature

Specifications

Level of multiplexing

Up to 800 targets

Recommended amount of starting material (Dependent on assay and sample type)

RNA: 1 ng–50 ng

DNA: 5 ng–300 ng

Protein: 250 ng–2.5 µg

Sample types supported

Total RNA, cell lysates in GITC, FFPE-derived total RNA, and PAXgene-lysed whole blood

Reaction Volume

Up to 35 µl

Limit of detection 0.5 fM spike-in control

15 zeptomole spike-in control

Fold change sensitivity

> 1.5-fold (if > 5 copies per cell)

> 2-fold (if > 1 copy per cell)

Spike correlation

R² ≥ 0.95

Linear dynamic range

6 x 10⁵ total counts

Throughput

12 lanes per 6 hours

Controls

Assay dependent

Feature

Specifications

Operating Temperature

18–28°C

Humidity

30–80% (non-condensing)

Pollution degree

2

Power source

100–240 VAC, 50–60 Hz

Dimensions

107 x 72 x 82 cm

Weight

81.65 kg

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Product

Description

Catalog Number


Unit Size

nCounter®
SPRINT
Profiler

Integrated system. Includes 1-year manufacturer’s warranty. One training kit is included with purchase.

NCT-SPRINT-1Y


System

Integrated system. Includes 1-year manufacturer’s warranty and 1-year service contract. One training kit is included with purchase.

NCT-SPRINT-2Y


System

Integrated system. Includes 1-year manufacturer’s warranty and 2-year service contract. One training kit is included with purchase.

NCT-SPRINT-3Y


System

Integrated system. Includes 1-year manufacturer’s warranty and 3-year service contract. One training kit is included with purchase.

NCT-SPRINT-4Y

System

Integrated system. Includes 1-year manufacturer’s warranty and 4-year service contract. One training kit is included with purchase.

NCT-SPRINT-5Y


System

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nCounter® Technology
nCounter® and Cancer Research
FFPE Samples with the nCounter® Analysis

For Research Use Only. Not for use in diagnostic procedures.