nCounter® PlexSet™ Reagents
Helping Your Research
Accelerate your cell line screening and high-throughput applications with nCounter PlexSet Reagents for Gene Expression Analysis. PlexSet technology enables multiplexed gene expression assays to be performed more efficiently and cost effectively for projects ranging up to 96 RNA targets. Unlike other gene expression technologies, PlexSet reagents enable researchers to reduce their hands-on time by eliminating the need for cDNA conversion, replicate utilization, or RNA purification. Like other nCounter assays, Plexset reagents provides a simple and robust method for multiplexing targets without the need to optimize probes or amplification conditions.
How It Works
The PlexSet reagents are based on proven nCounter technology utilizing molecular barcodes for highly multiplexed digital analysis.
Multiplex up to 96 custom probes (or choose from preselected pathway panels) across 96 samples to generate 9,216 data points per run with only 30 minutes of hands-on time
Utilization of lysed cells eliminates the need for RNA purification and amplification; save resources with an efficient workflow that does not require cDNA conversions, replicates, or prior probe optimizations
Proven nCounter Digital Gene Expression technology provides excellent precision and reproducibility across a wide dynamic range
Panel Selection Tool
Find the gene expression panel for your research with easy to use panel proFind Your Panel
Looking for recommendations on panels in your application area? Check out the NanoString Panel Pro selection tool. Browse our catalog of preselected pathway panels by name, application area, biologic pathway/process, or gene name(s).
- Expertly curated panels covering ~140 biological pathways and fields of interest for human, mouse, and rat samples.
- Each panel contains 90 genes chosen to comprehensively cover each pathway involved in the topic.
- All necessary controls and reference genes are included in each panel.
- Customize by adding additional genes of interest to the panels (or omitting genes that are not of interest).
Circadian dynamics of the teleost skin immune-microbiome interface.
Background: Circadian rhythms of host immune activity and their microbiomes are likely pivotal to health and disease resistance. The integration of chronotherapeutic approaches to disease mitigation in managed animals, however, is yet to be realised.
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF.
Rationale: αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs. Objectives: We evaluated multiple αv integrin inhibition strategies to assess which most effectively reduced fibrogenesis in explanted lung tissue from patients with idiopathic pulmonary fibrosis.
Glucocorticoid-Responsive Transcription Factor Krüppel-Like Factor 9 Regulates fkbp5 and Metabolism.
Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in zebrafish klf9 is expressed with GR-dependent oscillatory dynamics in synchrony with fkbp5, a GR target that encodes a negative feedback regulator of GR signaling.