Vantage 3D™ Assays
Helping Your Research
NanoString is pioneering the field of 3D Biology to accelerate the rate of research and maximize the amount of information that can be generated from a single sample. 3D Biology™ Technology is the ability to analyze combinations of RNA and protein simultaneously in a single experiment. Based on the NanoString digital barcode technology and designed for flexibility, the nCounter Vantage 3D Portfolio of assays provides a deeper view of cancer and immune biology and can be mixed and matched to answer a wide variety of biological questions.
How It Works
The nCounter Vantage 3D portfolio is designed for flexibility. Each panel can also be run as a stand-alone assay so you can generate the data you need. Select the right targeted panels for each analyte type, and detect and analyze them all at once with the nCounter Analysis System and nSolver™ software.
With the Vantage 3D portfolio, you can mix and match content based on your research needs with multi-analyte assays for Immuno-Oncology and Solid and Heme Tumor Profiling.
Panel Selection Tool
Find the gene expression panel for your research with easy to use panel proFind Your Panel
Vantage 3D RNA Panels
Vantage 3D Fusion Panels
Vantage 3D Protein Panels
Panel Compatibility and Customization
Each panel can be run as a stand-alone assay with customization available. Up to 24 user- defined genes can be added to any Vantage 3D RNA panel, including fusion panels. Up to five custom protein targets can be added to any Vantage 3D Protein panel using the Protein Barcoding Service.
Unsure if you can perform your desired experiment in a single lane? The table below provides an overview of analyte compatibility:
The spatial landscape of lung pathology during COVID-19 progression.
Recent studies have provided insights into the pathology and immune response to coronavirus disease 2019 (COVID-19)1–8. However, thorough interrogation of the interplay between infected cells and the immune system at sites of infection is lacking.
Spatial mapping of SARS-CoV-2 and H1N1 Lung Injury Identifies Differential Transcriptional Signatures.
Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. It is not clear if ARDS from SARS-CoV-2 is similar to that observed in Influenza H1N1, another common viral cause of lung injury.
In-silico performance, validation, and modeling of the Nanostring Banff Human Organ transplant gene panel using archival data from human kidney transplants
RNA gene expression of renal transplantation biopsies is commonly used to identify the immunological patterns of graft rejection. Mostly done with microarrays, seminal findings defined the patterns of gene sets associated with rejection and non-rejection kidney allograft diagnoses.