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nCounter® PanCancer
Immune Profiling Panel

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Helping Your Research

Gene expression profiling an be challenging because reproducibility and data analysis can be extremely demanding. The nCounter PanCancer Pathways Panel offers fast and high-throughput multiplex gene expression analysis solution for human or mouse genes. Each panel comes with 770 genes from 13 cancer-associated canonical pathways to support the understanding of basic cancer biology.

Pancancer immune profiling product area

How It Works

Perform multiplex gene expression analysis in human or mouse with 770 genes from 14 different immune cell types, common checkpoint inhibitors, and genes covering both the adaptive and innate immune response. The panel measures many features of the immune response to facilitate rapid development of clinically actionable gene expression profiles in the context of cancer immunotherapy.

01:

Comprehensive profiling of the immune response optimized for immuno-oncology research

02:

Identify tumor-infiltrating lymphocytes (TILs) for the tumor microenvironment

03:

Profile the expression of 30 CT antigens in humans

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Assess mechanistic pathway activity for single or combination studies

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Customizable with up to 55 additional user-defined genes with Panel Plus option

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Multi-analyte analysis with Vantage 3D™ Assays

The nCounter PanCancer Immune Profiling Panel is for cancer researchers that need more markers than is practical for RT-qPCR but don’t want the broad approach that next-gen sequencing (NGS) offers. The Panel is fully compatible with clinically relevant sample types such as fresh-frozen (FF) tissue, formalin-fixed, paraffin-embedded (FFPE) tumor sections, isolated immune cell populations such as PBMCs, and cell lysates. The panel may be used in conjunction with nCounter Panel Plus products for additional flexibility in experimental design.

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Product Information

Immune Cell Type Gene Coverage
Product Specifications
Immune Cell Type Gene Coverage
Product Specifications

Related Resources

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Whitepaper PanCancer Immune Profiling Advanced Analysis – Whitepaper
Product Bulletin Hallmarks of Cancer – Product Bulletin
Whitepaper Multiplexed Cancer Immune Response Analysis – Whitepaper

Publications

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Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma.

Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma.

Cross-site concordance evaluation of tumor DNA and RNA sequencing platforms for the CIMAC-CIDC network.

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