nCounter® Glial Profiling Panel

Helping Your Research

Comprehensively study the role of astrocytes, microglia, and oligodendrocytes in health and disease with the nCounter Glial Profiling Panel. Decipher the complex interplay between glial cells, peripheral immune cells, and neurons that underlies neurodegenerative & neuroinflammatory disorders and neurotrauma such as stroke, spinal cord injury, and traumatic brain injury.

How It Works

The Glial Profiling panel covers comprehensive glial cell biology involved in both homeostasis and disease and can be run on its own or paired with the Neuropathology or Neuroinflammation panels.

01:

Profile 770 human or mouse genes across 50+ pathways involved in glial cell biology:

Cell stress & Damage Response
Pathways Regulating Glia
Inflammation & Peripheral Immune Invasion
Glial Cell Homeostasis & Activation
Neurotransmission

02:

Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells

03:

Customizable with Panel Plus option – add up to 55 genes of your choice

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

Find Your Panel

Product Information

Functional Annotations

Cell Type Gene Coverage

Product Specifications

Catalog Information

Functional Annotations

Cell Type Gene Coverage

Product Specifications

Catalog Information

Related Resources

See All Resources

Product Bulletin Glial Panel – Product Bulletin

Flyer Glial Cell Publications – Flyer

Blog Rediscovering Microglia: Dr. Oleg Butovsky Discusses the Untapped Potential of Microglia in Neurodegenerative Diseases

Publications

View All Publications

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups.

The majority of supratentorial ependymomas in children contain oncogenic fusions, such as ZFTA-RELA or YAP1-MAMLD1. In contrast, posterior fossa (PF) ependymomas lack recurrent somatic mutations and are classified based on gene expression or methylation profiling into group A (PFA) and group B (PFB).

Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study.

The ability to investigate therapeutic interventions in animal models of neurodegenerative diseases depends on extensive characterization of the model(s) being used. There are numerous models that have been generated to study Alzheimer’s disease (AD) and the underlying pathogenesis of the disease.

Combination Treatment of CI-994 With Etoposide Potentiates Anticancer Effects Through a Topoisomerase II-Dependent Mechanism in Atypical Teratoid/Rhabdoid Tumor (AT/RT).

Purpose: Atypical teratoid/rhabdoid tumor (AT/RT) is arising typically in young children and is associated with a dismal prognosis which there is currently no curative chemotherapeutic regimen. Based on previous studies showing high histone deacetylase 1 (HDAC1) expression in AT/RT, the HDAC1 inhibitor CI-994 was used as a novel treatment strategy in this study.