Glial Profiling Panel
Helping Your Research
Comprehensively study the role of astrocytes, microglia, and oligodendrocytes in health and disease with the nCounter Glial Profiling Panel. Decipher the complex interplay between glial cells, peripheral immune cells, and neurons that underlies neurodegenerative & neuroinflammatory disorders and neurotrauma such as stroke, spinal cord injury, and traumatic brain injury.
How It Works
The Glial Profiling panel covers comprehensive glial cell biology involved in both homeostasis and disease and can be run on its own or paired with the Neuropathology or Neuroinflammation panels.
Profile 770 human or mouse genes across 50+ pathways involved in glial cell biology:
- Cell stress & Damage Response
- Pathways Regulating Glia
- Inflammation & Peripheral Immune Invasion
- Glial Cell Homeostasis & Activation
Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells
Customizable with Panel Plus option – add up to 55 genes of your choice
Panel Selection Tool
Find the gene expression panel for your research with easy to use panel proFind Your Panel
Targeted Transcriptomic Analysis of C57BL/6 and BALB/c Mice During Progressive Chronic Toxoplasma gondii Infection Reveals Changes in Host and Parasite Gene Expression Relating to Neuropathology and Resolution.
Toxoplasma gondii is a resilient parasite that infects a multitude of warm-blooded hosts and results in a lifelong chronic infection requiring continuous responses by the host. Chronic infection is characterized by a balanced immune response and neuropathology that are driven by changes in gene expression.
A research parasite’s perspective on establishing a baseline to avoid errors in secondary analyses.
To enhance reproducibility in scientific research, more and more datasets are becoming publicly available so that researchers can perform secondary analyses to investigate questions the original scientists had not posited. This increases the return on investment for the NIH and other funding bodies.
Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson’s disease.
Peripheral biomarkers indicative of brain pathology are critically needed for early detection of Parkinson’s disease (PD). In this study, using NanoString and digital PCR technologies, we began by screening for alterations in genes associated with PD or atypical Parkinsonism in erythrocytes of PD patients, in which PD-related changes have been reported, and which contain ~ 99% of blood α-synuclein.