nCounter®
Glial Profiling Panel

Helping Your Research

Comprehensively study the role of astrocytes, microglia, and oligodendrocytes in health and disease with the nCounter Glial Profiling Panel. Decipher the complex interplay between glial cells, peripheral immune cells, and neurons that underlies neurodegenerative & neuroinflammatory disorders and neurotrauma such as stroke, spinal cord injury, and traumatic brain injury.

Counter Glial Profiling

How It Works

The Glial Profiling panel covers comprehensive glial cell biology involved in both homeostasis and disease and can be run on its own or paired with the Neuropathology or Neuroinflammation panels.

01:

Profile 770 human or mouse genes across 50+ pathways involved in glial cell biology:

  • Cell stress & Damage Response
  • Pathways Regulating Glia
  • Inflammation & Peripheral Immune Invasion
  • Glial Cell Homeostasis & Activation
  • Neurotransmission
02:

Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells

03:

Customizable with Panel Plus option – add up to 55 genes of your choice

Panel Selection Tool

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Product Information

Product Specifications
Functional Annotations
Cell Type Gene Coverage
Catalog Information
Product Specifications
Functional Annotations
Cell Type Gene Coverage
Catalog Information

Related Resources

See All Resources
Product Bulletin Glial Panel – Product Bulletin
Flyer Glial Cell Publications – Flyer
Blog Post Rediscovering Microglia: Dr. Oleg Butovsky Discusses the Untapped Potential of Microglia in Neurodegenerative Diseases
Blog Post The Neuroinflammatory Puzzle of the Autoimmune Disease Multiple Sclerosis
Manual/Instructions NanoU Training Videos

Publications

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Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology

Posterior fossa type A (PF-EPN-A, PFA) ependymoma are aggressive tumors that mainly affect children and have a poor prognosis. Histopathology shows significant intratumoral heterogeneity, ranging from loose tissue to often sharply demarcated, extremely cell-dense tumor areas.

Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma

Stromal cells are key components of the tumour microenvironment (TME) and their incorporation into 3D engineered tumour-stroma models is essential for tumour mimicry. By engineering tumouroids with distinct tumour and stromal compartments, it has been possible to identify how gene expression of tumour cells is altered and influenced by the presence of different stromal cells.

Multiomic spatial landscape of innate immune cells at human central nervous system borders

The innate immune compartment of the human central nervous system (CNS) is highly diverse and includes several immune-cell populations such as macrophages that are frequent in the brain parenchyma (microglia) and less numerous at the brain interfaces as CNS-associated macrophages (CAMs). Due to their scantiness and particular location, little is known about the presence of temporally and spatially restricted CAM subclasses during development, health and perturbation.

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