nCounter® NHP Immunology Panel
Helping Your Research
Non-Human Primate (NHP) research is critical to provide insight into the functionality of drugs and vaccines in development. Studies with NHPs are costly and produce a plethora of samples: extracting the maximal biological information out of a given sample in a cost-effective and robust manner becomes key. NanoString’s nCounter barcoding technology provides an ideal solution; you can directly quantify hundreds of transcripts from multiple sample types with minimal hands-on time, and the data is very reproducible.
Comparison of Transcriptomic Platforms for Analysis of Whole Blood from Ebola-Infected Cynomolgus Macaques
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Functional annotations for 18 immune-related signaling pathways were assigned across all genes in the NHP Immunology panel, allowing for a comprehensive and functional view of the NHP immune response.
Publications
Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates
Invasive bacterial infections during pregnancy are a major risk factor for preterm birth, stillbirth, and fetal injury. Group B streptococci (GBS) are Gram-positive bacteria that asymptomatically colonize the lower genital tract but infect the amniotic fluid and induce preterm birth or stillbirth.
Innate Immune Responses to Chimpanzee Adenovirus Vector 155 Vaccination in Mice and Monkeys.
Immune outcomes of Zika virus infection in nonhuman primates.
Although the Zika virus (ZIKV) epidemic is subsiding, immune responses that are important for controlling acute infection have not been definitively characterized. Nonhuman primate (NHP) models were rapidly developed to understand the disease and to test vaccines, and these models have since provided an understanding of the immune responses that correlate with protection during natural infection and vaccination.
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