nCounter® Myeloid Innate Immunity Panel

Helping Your Research

The nCounter® Myeloid Innate Immunity Panel provides comprehensive coverage of myeloid-derived cells in a targeted gene expression assay. These panels can be used with multiple sample types like peripheral blood mononuclear cells (PBMCs) or formalin-fixed paraffin-embedded (FFPE) tissue sections and provide results in less than 24 hours with minimal hands-on time and data analysis.

The Myeloid Innate Immunity Panel is designed to encompass all aspects of the innate immune response of myeloid-derived cells and can be used for basic and translational research in immuno-oncology, autoimmunity, and infectious disease. The panel is curated to include the most current and relevant genes and is available in both human and mouse versions. Use the Myeloid Innate Immunity Panel to study:

Mechanisms of immune evasion
Damage response, wound healing & tissue repair
Immune regulation
Disease pathogenesis
Treatment response vs. non-response

How It Works

The nCounter Myeloid Innate Immunity Panels were developed in collaboration with leading experts in the field of immuno-oncology but can be used to study the role of myeloid-derived cells whenever the innate immune system is implicated in the response to a disease or pathogen. Each panel enables characterization of the innate immune response by profiling genes involved in the recruitment and activation of selected myeloid subtypes.

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770 genes In 19 different pathways and processes across 7 different myeloid cell types

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Rapidly analyze Complex immune responses with publication-quality results next day

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Optimized for difficult sample types including FFPE, PBMCs, or FACS sorted cells

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Genes represent all major myeloid cell types including neutrophils, eosinophils, mast cells, dendritic cells, monocytes, and macrophages with 19 functional and pathway annotations

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Customize with Panel Plus to spike-in up to 55 genes of your choice to tailor the panel for your research project

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

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Product Information

Specifications

Catalog Information

Specifications

Catalog Information

Related Resources

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Product Bulletin Myeloid Innate Immunity Panel – Product Bulletin

Publications

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NanoString Technology for Human Papillomavirus Typing.

High-throughput HPV typing assays with increased automation, faster turnaround and type-specific digital readout would facilitate studies monitoring the impact of HPV vaccination. We evaluated the NanoString nCounter((R)) platform for detection and digital readout of 48 HPV types in a single reaction.

Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation.

PURPOSE: Patients with heterozygous gain-of-function (GOF) mutations in STAT1 frequently exhibit chronic mucocutaneous candidiasis (CMC), immunodeficiency and autoimmune manifestations. Several treatment options including targeted therapies and hematopoietic stem cell transplantation (HSCT) are available for STAT1 GOF patients but modalities and outcomes are not well established.

Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses.

Endothelial cells (EC) coordinate vascular homeostasis and inflammation. In organ transplantation, EC are a direct alloimmune target.

Support Documents

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nCounter Hs Myeloid Innate Immunity V2 nCounter Mm Myeloid Innate Immunity V2 nCounter PlexSet Preselected Pathway Panel IO Myeloid Activity Human-Mouse Gene List Hs Myeloid V2.0 RLF

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