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nCounter® Metabolic Pathways Panel

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Helping Your Research

Quantify the expression of hundreds of genes involved in core metabolic processes and immunometabolism for human or mouse samples in a reliable, simple, and robust way using the nCounter Metabolic Pathways Panel. Understand the complex mechanisms behind metabolic adaptation, metabolic switching, metabolic alterations, and study changes in mitochondrial respiration and glycolysis.

The Metabolic Pathways Panel helps advance efforts towards novel therapeutic targets that take advantage of altered metabolism in cancer and other diseases. Get results in less than 24 hours from multiple sample types with a workflow that maximizes insight and minimizes turnaround time:

  • Quantify the presence and relative abundance of 14 different immune cell types for immunometabolism studies
  • Bypass RT and amplification by direct detection, yielding highly reproducible data
  • Process your samples with < 30 minutes hands-on time and get results in < 24 hours

How It Works

The underlying molecular mechanisms behind alterations in metabolic pathways, signaling pathways, and cell stress can now be fully elucidated, giving you a complementary tool to traditional metabolite assays for profiling metabolic checkpoints and potential therapeutic targets.

Directly profile 768 genes in human or mouse across 34 annotated pathways involved in five important themes for metabolism research:

01:

Biosynthesis and Anabolic Pathways

02:

Nutrient Capture and Catabolic Pathways

03:

Cell Stress

04:

Metabolic Signaling

05:

Transcriptional Regulation

Panel Selection Tool

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Product Information

Gene Coverage Across Core Metabolic Themes
Functional Annotations
Immune Cell Profiling
Product Specifications
Catalog Information
Gene Coverage Across Core Metabolic Themes
Functional Annotations
Immune Cell Profiling
Product Specifications
Catalog Information

Related Resources

See All Resources
Product Bulletin Metabolic Pathways Panel – Product Bulletin
Blog Q&A with Metabolic Pathways Panel Grant Winner Teresa Cardoso Delgado, Ph.D.: The Metabolomics of Non-Alcoholic Fatty Liver Disease (NAFLD)
Webinar Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells
Webinar Hepatic transcriptional profiling in mouse models of Non-Alcoholic Fatty Liver Disease (NAFLD)

The spatial landscape of lung pathology during COVID-19 progression.

Recent studies have provided insights into the pathology and immune response to coronavirus disease 2019 (COVID-19)1–8. However, thorough interrogation of the interplay between infected cells and the immune system at sites of infection is lacking.

Spatial mapping of SARS-CoV-2 and H1N1 Lung Injury Identifies Differential Transcriptional Signatures.

Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. It is not clear if ARDS from SARS-CoV-2 is similar to that observed in Influenza H1N1, another common viral cause of lung injury.

In-silico performance, validation, and modeling of the Nanostring Banff Human Organ transplant gene panel using archival data from human kidney transplants

RNA gene expression of renal transplantation biopsies is commonly used to identify the immunological patterns of graft rejection. Mostly done with microarrays, seminal findings defined the patterns of gene sets associated with rejection and non-rejection kidney allograft diagnoses.

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