GeoMx™ Digital Spatial Profiler Publications

Featured Publications


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Balko J, et al.

A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis. Nature Medicine 2019
First application in assessing immune toxicity

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Van TM, Blank C

A user's perspective on GeoMxTM digital spatial profiling. Immuno-Oncology Technology 2019
First Beta User experience captured

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Rimm D, et al.

High-plex predictive marker discovery for melanoma immunotherapy treated patients using Digital Spatial Profiling. CCR epub 2019
Demonstrates novel strategy for biomarker discovery

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Wargo J, et al.

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med 2018; 24(11): 1649-54.
First publication on biomarker discovery application

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Blank CU, et al.

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma. Nat Med 2018; 24: 1655-1661.
First publication on biomarker discovery application

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Ihle C, et al.

Distinct tumor microenvironment of lytic and blastic bone metastases in prostate cancer patients. JITC 2019; 7: 293.
First GeoMx DSP publication Journal for ImmunoTherapy of Cancer

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Rozeman EA, Prevoo W, et al.

Phase Ib/II trial testing combined radiofrequency ablation and ipilimumab in uveal melanoma (SECIRA-UM). Melanoma Res. 2019 Dec. 26; 10.1097.
New GeoMx DSP publication

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Farren MR, Sayegh L, et al.

Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemo- and radiotherapy. JCI Insight 2019 Dec 12; 130362: 10.1172.
New GeoMx DSP publication in JCI Insight

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Helmink B, Wargo J, et al.

B-cells and tertiary lymphoid structures (TLS) contribute to immune checkpoint blockade response. Nature 2020; 7: 293.
Second GeoMx DSP paper from Wargo group

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Cabrita R, Jönsson G, et al.

Tertiary lymphoid structures improve melanoma survival and immunotherapy response. Nature 2020; 7: 293.
New GeoMx DSP publication in Nature