GeoMx® Digital Spatial Profiler Publications

Featured Publications


McCart Reed, A.E., Bennett, J., Kutasovic, J.R. et al.

Digital spatial profiling application in breast cancer: a user’s perspective. Virchows Arch (2020)


Keam SP, Halse H, Nguyen T, et al.

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot. J Immunother Cancer. 2020;8(1)


Vadakekolathu J, Minden MD, Hood T, et al.

Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia Sci Transl Med. 2020;12(546):eaaz0463. doi:10.1126/scitranslmed.aaz0463


Merritt CR, Ong GT, Church SE et al.

Multiplex digital spatial profiling of proteins and RNA in fixed tissue. Nat Biotechnol 202;38:586–599.


Mceachin ZT, Gendron TF, Raj N, et al.

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36. Neuron. 2020; epub ahead of print.


Gupta S, Zugazagoitia J, Martinez-morilla S, Fuhrman K, Rimm DL.

Digital quantitative assessment of PD-L1 using digital spatial profiling. Lab Invest. 2020; epub ahead of print.


Cabrita R, Lauss M, Sanna A, et al.

Tertiary lymphoid structures improve immunotherapy and survival in melanoma. Nature. 2020;577(7791):561-565.


Helmink BA, Reddy SM, Gao J, et al.

B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020;577(7791):549-555.


Rozeman EA, Prevoo W, Meier MAJ, et al.

Phase Ib/II trial testing combined radiofrequency ablation and ipilimumab in uveal melanoma (SECIRA-UM). Melanoma Res. 2020;30(3):252-260.


Ihle CL, Provera MD, Straign DM, et al.

Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients. J Immunother Cancer. 2019;7(1):293.


Johnson DB, Mcdonnell WJ, Gonzalez-ericsson PI, et al.

A case report of clonal EBV-like memory CD4 T cell activation in fatal checkpoint inhibitor-induced encephalitis. Nat Med. 2019;25(8):1243-1250.


Van TM, Blank CU.

A user's perspective on GeoMx digital spatial profiling. IOTECH. 2019;1:11-18.


Toki MI, Merritt CR, Wong PF, et al.

High-Plex Predictive Marker Discovery for Melanoma Immunotherapy-Treated Patients Using Digital Spatial Profiling. Clin Cancer Res. 2019;25(18):5503-5512.


Blank CU, Rozeman EA, Fanchi LF, et al.

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma. Nat Med. 2018;24(11):1655-1661.


Amaria RN, Reddy SM, Tawbi HA, et al.

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018;24(11):1649-1654.