GeoMx® Digital Spatial Profiler

The Spatial Biology Solution


Helping Your Research

Understanding tissue heterogeneity is critical to answering key biological questions. The current tissue analysis paradigm requires a tradeoff between low-plex spatial analysis or high-plex bulk analysis, sacrificing valuable information and consuming precious samples. NanoString’s GeoMx Digital Spatial Profiler (DSP) combines the best of spatial and molecular profiling technologies by generating digital whole transcriptomes and profiling data for 100s of validated Protein analytes from up to 12 tissue slides per day. This unique combination of high-plex and high-throughput spatial profiling enables researchers to rapidly and quantitatively assess the biological implications of the heterogeneity within tissue samples.  From discovery to translational research, the GeoMx DSP is the most flexible and robust spatial solution designed to conform to your ever-changing research needs. 

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Any Target
Any Region
Any Sample
Any Target
Any Region

Resolve tissue heterogeneity with intelligent, flexible region of interest (ROI) selection based on the biology of the sample.
Any Sample

Access to more samples with robust data from the most challenging sample types, including Formalin-Fixed Paraffin-Embedded and Fresh Frozen tissue.


How it Works

The GeoMx DSP data center provides an end-to-end software solution from image acquisition, region of interest selection to a fully integrated data analysis experience.

in Your Lab

Webinar: Delivering on
the Promise of Spatial Genomics

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Product Information

Robust, Automated Workflow
Catalog Information
Robust, Automated Workflow

Catalog Information

GeoMx Digital Spatial Profiler

Related Resources

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Tradeshow/Conference 3rd Annual
Spatial Genomics Summit
Brochure/eBook GeoMx DSP – Brochure
Product Bulletin GeoMx Cancer Transcriptome Atlas (CTA) – Product Bulletin
Whitepaper GeoMx COVID-19 Applications – Whitepaper

GeoMx Publications

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The spatial landscape of lung pathology during COVID-19 progression.

Recent studies have provided insights into the pathology and immune response to coronavirus disease 2019 (COVID-19)1–8. However, thorough interrogation of the interplay between infected cells and the immune system at sites of infection is lacking.

GeoMx RNA Assay: High Multiplex, Digital, Spatial Analysis of RNA in FFPE Tissue.

RNA in situ hybridization (ISH) is a widely used technique for the localization of mRNA in tissues. Limitations to traditional ISH include the number of targets that can be analyzed concurrently and the ability for many of these assays to be used in formalin-fixed, paraffin-embedded tissues (FFPE).

Spatial mapping of SARS-CoV-2 and H1N1 Lung Injury Identifies Differential Transcriptional Signatures.

Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. It is not clear if ARDS from SARS-CoV-2 is similar to that observed in Influenza H1N1, another common viral cause of lung injury.


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