GeoMx®
Cancer Transcriptome Atlas

Curated Content for Cancer Biology

The GeoMx Cancer Transcriptome Atlas (CTA) is designed for comprehensive profiling of the tumor, tumor microenvironment, and tumor immune status. Profile over 1,800 RNA targets simultaneously with spatial resolution in any region of interest from a single tissue section using the GeoMx Digital Spatial Profiler (DSP).

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Product Highlights

  • Comprehensive RNA content designed for cancer biology research
    • Includes coverage of the global immune response, microenvironment immune activity, tumor reactivity, Tumor Inflammation Signature (TIS)1, and PAM50
    • Over 50 pathways to explore all aspects of cancer and tumor biology
  • Compatible with RNAscope® and antibody visualization markers
  • Supplement with up to 30 additional targets of interest
  • For use with next-generation sequencer (NGS) readout and compatible with DSP Data Center Software

Over 50 pathways included in the CTA

 

Annotation Genes Annotation Genes Annotation genes
Angiogenesis 51 DNA Damage Repair 155 mTOR Signaling 35
Antigen Presentation 104 ECM Organization 126 Myeloid Activity 174
Apoptosis 62 EMT 81 Neutrophil Activation 120
Autophagy 14 Epigenetic Regulation 58 NK-kB Signaling 105
BCR Signaling 79 Fc Receptor Signaling 63 NK Cell Activation 108
C-type Lectin Activation 64 FoxO Signaling 82 Notch Signaling 78
cAMP Signaling 68 Hedgehog Signaling 49 Nucleic Acid Sensing 80
Carbon Metabolism 48 Hippo Signaling 71 PDGF Signaling 34
Cell Adhesion 207 Hypoxia 73 PI3K-Akt 226
Cell Adhesion Signaling 117 Insulin Signaling 64 Proteotoxic Stress 11
Cell Cycle 139 Interferon Signaling 89 Regulation of Cell Motility 90
Chemokine Signaling 119 Interleukin Signaling 205 TCR Signaling 52
Circadian Clock 19 JAK-STAT Signaling 115 TGF-beta Signaling 65
Complement System 43 Lymphocyte Regulation 89 TLR Signaling 90
Costimulatory Signaling 48 Lymphocyte Trafficking 43 Transcriptional Misregulation 118
CT Antigens 31 MAPK Signaling 220 Type I Interferon Signaling 48
Cytosolic DNA-sensing 30 Matrix Remodeling and Metastasis 115 Type II Interferon Signaling 49
Cytotoxicity 108 Metabolism 174 Wnt Signaling 128
Death Receptor Signaling 118        

 

For Research Use Only. Not for use in diagnostic procedures.