This 770-gene multiplex panel provides analysis of the links between known disease associated mutations and gene expression, allowing researchers to identify new gene functions and to look at gene expression in response to treatment.
- Discovery tool for disease-associated mutation gene function and biomarker characterization
- Comprehensive content with variants across nine of the top autoimmune diseases
- Gene expression profiling of immune response together with gene mutations
- Customizable with panel-plus option – add up to 30 user-defined genes
- Workflow is simple, user-friendly, and efficient with just 15 minutes total hands-on time
Disease specific annotations for nine autoimmune disease types and human immune response genes were assigned across all genes in the autoimmune discovery panel allowing for the identification of gene functions and signatures for all autoimmune diseases.
|Disease Type Association||Description||Genes|
|Multiple Sclerosis||Demyelinating disease of the nervous system||104|
|Rheumatoid Arthritis||Chronic inflammatory disorder of joints||95|
|Systemic Lupus Erythematosus||Inflammation and damage to various body tissues||55|
|Type 1 Diabetes||Disease that causes damage to beta cells in the pancreas||44|
|Ankylosing Spondylitis||Chronic inflammatory disorder of the spine||43|
|Celiac Disease||Immune response to gluten that damages small intestine||249|
|Ulcerative Colitis||Disease causing inflammation and ulcers in large intestine||200|
|Inflammatory Bowel Disease||Inflammation of the digestive tract||249|
|Psoriasis||Deficiency in function of multiple endocrine glands||48|
|Other Immune Response||Human immune response genes||237|
|Number of Targets||770 (Human) including internal reference genes|
|Standard Input Material (No amplification required)||25 ng-300 ng|
|Sample Type(s)||FFPE-derived RNA, total RNA, fragmented RNA, cell lysates, PBMCs, whole blood/plasma, urine, saliva, cerebral spinal fluid, synovial fluid|
|Customizable||Add up to 30 unique genes with Panel-Plus|
|Time to Results||Approximately 24 hours|
|Data Analysis||nSolver Analysis Software|
Panel on Demand
The Autoimmune Discovery Panel is now available as a Panel on Demand. Using the identical or modified gene list NanoString can create a panel for your individual needs. Please contact your local sales representative or send your request to us at firstname.lastname@example.org.
For Research Use Only. Not for use in diagnostic procedures.