New discovery tool to better understand the links between known disease associated mutations and gene expression, which allows researchers to identify new gene functions and to look at gene expression in response to treatment. This panel consists of 770 genes that cover known disease associated gene mutations for nine of the top autoimmune diseases in addition to a selection of genes with known function in human immune response.
- Discovery of disease-associated mutation gene function and biomarker characterization
- Comprehensive gene collection representing variants across nine of the top autoimmune diseases
- Gene expression profiling of immune response together with gene mutations
- Customizable with panel-plus option – add up to 30 user-defined genes
- nCounter workflow is simple, user-friendly, and efficient with just 15 minutes total hands-on time
Disease specific annotations for nine autoimmune disease types and human immune response genes were assigned across all genes in the autoimmune discovery panel allowing for the identification of gene functions and signatures for all autoimmune diseases.
|Disease Type Association||Description||Genes|
|Multiple Sclerosis||Demyelinating disease of the nervous system||104|
|Rheumatoid Arthritis||Chronic inflammatory disorder of joints||95|
|Systemic Lupus Erythematosus||Inflammation and damage to various body tissues||55|
|Type 1 Diabetes||Disease that causes damage to beta cells in the pancreas||44|
|Ankylosing Spondylitis||Chronic inflammatory disorder of the spine||43|
|Celiac Disease||Immune response to gluten that damages small intestine||249|
|Ulcerative Colitis||Disease causing inflammation and ulcers in large intestine||200|
|Inflammatory Bowel Disease||Inflammation of the digestive tract >||249|
|Polyglandular Syndrome||Deficiency in function of multiple endocrine glands||49|
|Other Immune Response||Human immune response genes||237|
|Number of Targets||770 (Human) including internal reference genes|
|Standard Input Material (No amplification required)||25 ng-300 ng|
|Sample Type(s)||FFPE-derived RNA, total RNA, fragmented RNA, cell lysates, PBMCs, whole blood/plasma, urine, saliva, cerebral spinal fluid, synovial fluid|
|Customizable||Add up to 30 unique genes with Panel-Plus|
|Time to Results||Approximately 24 hours|
|Data Analysis||nSolver Analysis Software|
|Product||Product Description||Quantity||Catalog Number|
|nCounter Human Autoimmune Discovery Panel||Includes 770 genes, including 15 internal reference genes for data normalization||12 Reactions||XT-CSO-HAID1-12|
Consortium Gene Expression Panels
Consortium panels are created with leaders, working groups, and global consortiums. These products may be available in limited quantities and the gene content is subject to future change.
If you are part of a consortium or working group or have a specific need you would like NanoString to consider for panel development, please contact us at firstname.lastname@example.org.
For Research Use Only. Not for use in diagnostic procedures.