Upcoming Shows & Events

Alzheimer's Association International Conference (AAIC)

NanoString Booth #226

DATE:

Jul 14, 2019 - Jul 17, 2019

LOCATION: Los Angeles Convention Center
1201 S. Figueroa St.
Los Angeles, CA 90015

Learn more about GeoMx DSP and join us for a live software demo.

3:30 PM (Sun, Tue), 9:30 AM (Mon, Wed)

Highlighted Posters:

Monday, July 15th

P2-105: A Novel Systems Biology Approach to Evaluate Mouse Models of Late Onset Alzheimer’s Disease: nCounter Mouse AD Panel

Carter, et al., The Jackson Laboratory

P2-133: Initial Characterization of Novel Mouse Models of Late Onset Alzheimer’s Disease Based on Human Genetic Associations

Howell, et al., The Jackson Laboratory

P2-104: Precise Morphological Mapping of High Plex Neurodegenerative and Neuroinflammation Protein Targets in Human FFPE Brain Tissue with the GeoMx™ Digital Spatial Profiler

Rosenbloom, et al., NanoString Technologies

P2-185: Characterizing Neuroinflammatory Responses in Apoliprotein E Genotypes

Kloske, et al., University of Kentucky

Tuesday, July 16th

P2-151: Brain microRNAs Associated with Late-Life Depression Are Also Linked to Cognitive Trajectory and Dementia

Wingo, et al., Emory University

P2-054: Assessing the Efficacy and Safety Profile of Class C CpG ODN in a Non-Human Primate Model of Sporadic Caa

Patel, et al., New York University School of Medicine

Wednesday, July 17th

04-09-02: Regulation of Pro-Inflammatory and Disease-Associated Microglial Activation of Bin1

Gao, et al., Emory University

P4-474: Characterization of a novel humanized wild-type tau expressing model in high-amyloid background of 5xFAD mice

Cynis, et al., Fraunhofer Institute for Cell Therapy and Immunology

Assays for Neuroscience Research

Improving Translational Alzheimer’s Disease Research

Make studies in Alzheimer’s Disease (AD) models and human tissue more reproducible and more translationally relevant with analysis of expression profiles shown to be relevant for clinical disease. Developed in collaboration with MODEL-AD, the nCounter AD Panels assays AD phenotypes and disease progression for use in mouse model development, in vivo screening of potential therapeutics, and human tissue characterization.

Profile Neuroinflammation Pathways and Processes

nCounter Neuroinflammation Panels are designed to rapidly analyze important aspects of neuroimmune interactions for a complete view of the complex interplay between the immune and nervous systems. The human and mouse panels provide comprehensive evaluation of 23 pathways, processes, and 19 cell types that are involved in neuroinflammation.

Assess Neurodegenerative Disease and Pathogenesis

The nCounter Neuropathology panels are designed to encompass all aspects of neurodegeneration for use in basic and translational research. The human and mouse panels provide an effective means to comprehensively evaluate neurodegeneration and research the pathogenesis of all types of neurodegenerative diseases, including cell profiling five important cell types including neurons, astrocytes, microglia, oligodendrocytes and endothelial cells.

Morphology Driven Multi-Analyte Analysis

Immunohistochemistry and immunofluorescence have been used to assess spatial heterogeneity of proteins and nucleic acids in tissue slices. However, these techniques have limited multiplexing capability. GeoMx™ Digital Spatial Profilier combines immunofluorescence techniques with digital optical barcoding technology to perform highly multiplexed, spatially resolved RNA or protein profiling experiments.

Learn more at https://www.nanostring.com/scientific-content/neuroscience-research