NanoString Blog

Category: Spatial Transcriptomics

Multiomics Spatial Analysis Spatial Biology Spatial Transcriptomics

GeoMx® DSP Spatial Proteogenomics datasets now available on Illumina® BaseSpace™ Sequence Hub

NanoString and Illumina have collaborated to release two new demo datasets of GeoMx Digital Spatial Profiler (DSP) data on the Illumina BaseSpace Sequence Hub (BSSH) cloud.  Spatial proteogenomics enables new…

Megan Vandenberg, Margaret Hoang and Sophie Wehrkamp-Richter / September 14, 2023

Spatial Transcriptomics

What is transcriptomics?

The transcriptome is the sum of all the RNA in an organism’s cells and tissues being actively transcribed at any given time from genomic DNA. It includes protein-coding messenger RNA (mRNA)…

Nirupama Deshpande / July 5, 2023

Spatial Transcriptomics

An Integrated Omics Approach: The Human Protein Atlas

Although humans have been using atlases for thousands of years, the word atlas was first coined in 1595 by the Flemish map maker Gerardus Mercator. In geographical terms, an atlas…

Nirupama Deshpande / June 27, 2023

Spatial Transcriptomics

What is the human protein atlas used for?

In order to understand the role of each protein in various biological processes such as cell organization, signaling pathways, or disease mechanisms, it becomes essential to study protein expression with…

Nirupama Deshpande / June 26, 2023

Digital Spatial Profiling GeoMx DSP Spatial Transcriptomics

FFPE Genomics: a Portal Into the World of Transcriptomic Research?

The emergence of spatial transcriptomics, with its ability to generate highly detailed maps of gene expression with spatial context, is revolutionizing biomedical research, particularly in developmental biology, cancer, immunology, and…

Nirupama Deshpande / June 21, 2023
Detail of a syringe needle in a vial

CosMx SMI Spatial Transcriptomics

Common questions in molecular biology: What are the most common biomarkers?

If you stopped someone on the street and asked them to give you an example of a common biomarker, you will more than likely be met with silence. However, if…

Geoffrey Hummelke / June 12, 2023
Green-outlined cells on a dark background, with pink/purple splotches in each cell

CosMx SMI Spatial Transcriptomics

A Spatial Twist on Biomarkers: Using Spatial Transcriptomics for Biomarker Discovery

Anyone who studies biology knows that living systems are highly complex, sophisticated entities, often containing redundant processes. Sorting out the mechanisms at play in any biological system is therefore aided…

Geoffrey Hummelke / June 6, 2023
The first fully integrated single-cell spatial biology solution

CosMx SMI Spatial Biology Spatial Transcriptomics

What’s New at NanoString for 2023: The Arrival of the First Fully Integrated Single-Cell Spatial Solution

One of the interesting hallmarks of celebrating the start of a new year is the consumption of special foods. For example, in the American South Hoppin’ John, or black-eyed peas,…

Melanie Peffer / December 15, 2022

Multiomics Spatial Analysis Spatial Transcriptomics

Integrated Spatial Multiomics Deconvolve Multicellular Dynamics in Pancreatic Cancer

In an extraordinary team effort led by the Center for Systems Biology at Harvard Medical School, in collaboration with NanoString, scientist Will Hwang and colleagues used integrated spatial multiomic and…

Laura Tabellini Pierre / October 25, 2022
Spatial Transcriptomics

Digital Spatial Profiling Multiomics Spatial Analysis Spatial Transcriptomics

Spatial Multiomics Identifies New Actionable Therapeutic Targets

Pancreatic cancer represents 3% of the overall cancers in America and yet is responsible for 7% of all cancer deaths. The five-year relative survival rate – the cancer-related death rate…

Laura Tabellini Pierre / October 4, 2022
Green-outlined cells on a dark background, with pink/purple splotches in each cell

CosMx SMI Spatial Molecular Imaging Spatial Transcriptomics

Spatial Multiomics Single-Cell Imaging Platform to Explore FFPE Tissues with Spatial Context

What is Spatial Multiomics? Spatial multiomics describe the ability to locate and quantify DNA, RNA, and protein in the three-dimensional space of a tissue. Decades of research have built a…

Geoffrey Hummelke / September 6, 2022

Spatial Transcriptomics

Understanding Spatial Sequencing in the Context of Spatial Biology

What is spatial sequencing? Spatial sequencing is viewing a specific area or a region within a tissue, then sequencing all transcripts found in that region. Spatial sequencing allows the user…

NanoString / July 28, 2022