NanoString Blog

Category: Immunology

Oncology protein rendering

Immunology nCounter Oncology

TIS GEP: Use Cases in Sample Stratification, Assessment of Treatment Effect, and as a Component of a Multivariate Biomarker

Introduction to the TIS Gene Expression Profile Innovations in multiplex gene expression analysis are revolutionizing translational research and clinical practices by enabling identification of gene signatures involved in various biological…

Espy Anguiano / October 10, 2023

Immunology Infectious Disease Oncology

T-Cell Receptor Diversity…What Are You Missing?

The T cell receptor (TCR) is one of the distinguishing molecules of the adaptive immune system. TCRs allow mammalian immune systems to recognize and respond to foreign entities (pathogens, vaccines,…

Trena Cormier / November 15, 2021

Immunology Infectious Disease nCounter

How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses

In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…

Melanie Peffer / October 5, 2021

Immunology Infectious Disease nCounter

How nCounter helps vaccine research: Part 1, Improving Vaccines

I really dislike needles. In fact, I’m downright needle-phobic.  When I was notified of my eligibility to receive my COVID-19 vaccine, it was without a doubt the most excited I…

Melanie Peffer / September 27, 2021
3d model of a celular structure

Immunology Infectious Disease

COVID-19 Pathogenesis Steps Out of the Shadows

“Analysis of pulmonary vessels showed that widespread thrombosis with microangiopathy ─ a severe condition wherein small blood clots are formed within the tiniest of blood vessels ─ was 9x more…

Laura Tabellini Pierre / July 20, 2020
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Immunology Oncology

Why is Spatial Transcriptomics Critical to Studying Sarcomas? Q&A with Dr. Troy McEachron, Ph.D

“Whereas the EWS specimens tended to have very simple genomes, the osteosarcoma specimens looked like a hand grenade had gone off in the genome. These were the most fragmented and…

Laura Tabellini Pierre / June 15, 2020
Blue background of cells

Autoimmunity Immunology

How to Resolve the Complexity of Autoimmune Diseases

What are Autoimmune Diseases? Autoimmune diseases are chronic inflammatory conditions, life-long debilitating illnesses with increased mortality, and high healthcare costs for therapy and care. They are systemic conditions characterized by…

Laura Tabellini Pierre / September 16, 2019
autoimmune rendering

Autoimmunity Immunology

Q&A with Dr. Oliver Brain: Unintended Consequences Create a Unique Opportunity to Study Inflammatory Bowel Disease.

Oliver Brain, MRCP, PhD, is a principal investigator at the University of Oxford, Nuffield Department of Clinical Medicine, and a recent winner of an nCounter® Autoimmune Profiling Panel through a…

Robin Lynn White / June 3, 2019