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Category: Digital Spatial Profiling

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Rendering of oncology proteins

Digital Spatial Profiling nCounter Oncology

New approaches to CAR-T therapy

What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…

Nirupama Deshpande / January 18, 2022
3d model of a neuron

Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics

Neurodegenerative disorders and Parkinson’s disease.

The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…

Nirupama Deshpande / December 6, 2021

Digital Spatial Profiling Spatial Biology

The Importance of Segmentation in Spatial Biology

In a highly interconnected world, clear communication and information across the globe are critical. The same is true at the tissue and cellular levels. Cells communicate through chemical signals such…

Laura Tabellini Pierre / October 29, 2021
panel plus

Digital Spatial Profiling GeoMx Spatial Transcriptomics

Spatial Transcriptomics: Birth of GeoMx® Digital Spatial Profiler

“A rose started off a bud, a bird started off an egg, and a forest started off a seed.” (Matshona Dhliwayo, author and philosopher). It may seem odd, but the…

Laura Tabellini Pierre / May 24, 2021
Spatial Transcriptomics

Digital Spatial Profiling Spatial Biology

Why Spatial Biology?

Spatial Transcriptomics is used to determine subcellular localization of mRNA molecules. NanoString explains how this data enhances research.

Laura Tabellini Pierre / April 10, 2021
Spatial Transcriptomics

Digital Spatial Profiling GeoMx Spatial Molecular Imaging Spatial Transcriptomics

Spatial Biology named Method of the Year by Nature Methods

Established in 2007, the Nature Methods’ “Method of Year” feature has covered the most revolutionary methodological developments in life science research.   Starting in 2007, the Method of Year winner was,…

Karrie Spitzer / March 29, 2021
Coffee blue background

Digital Spatial Profiling Q&A Services and Core Labs

Excellence, Cooperation, and Passion Come Together to Serve the Scientific Community. Q&A with Dr. Peter O’Toole, Director of the Bioscience Technology Facility, University of York.

Dr. Peter O’Toole, Ph.D., is the director of the Bioscience Technology Facility at the University of York in England, where he established and still leads the Imaging and Cytometry Laboratory, one of the…

Laura Tabellini Pierre / August 3, 2020
Checkpoint inhibitors

Digital Spatial Profiling Q&A

Q&A with Dr. Aubrey Thompson, Ph.D.: The GeoMx® Digital Spatial Profiler is Turning the Tables on Breast Cancer

E. Aubrey Thompson, Ph.D is a Professor in the Department of Cancer Biology at the Mayo Clinic in Jacksonville, FL. His research focuses on breast cancer and using genomic and…

Laura Tabellini Pierre / April 27, 2020
Blue background of cells in a bloodstream

Digital Spatial Profiling Events

Stories of Remarkable Technological Advances at AGBT 2020

The Advances in Genome Biology and Technology conference celebrated its 20th-anniversary event this February, and what a dramatic range of advances have occurred in our field since the first meeting!…

Laura Tabellini Pierre / March 30, 2020
Blue background of cells

Autoimmunity Digital Spatial Profiling Neuroscience Oncology

Readers’ Favorite Webinars: A Year in Review

NanoString webinars allow you to sit back, relax and listen to a leader in the field talk about his/her research and/or answer your questions.  They have always been a crowd-pleaser,…

Laura Tabellini Pierre / March 2, 2020
Checkpoint inhibitors

Digital Spatial Profiling

Redefining Precision: Why Spatial Resolution Matters

Functional annotation of gene and protein expression is a crucial step in deciphering cellular mechanisms. Traditional transcriptomic and proteomic assays are done in bulk, where RNA and proteins from different…

Laura Tabellini Pierre / February 17, 2020
Tissue analysis

Digital Spatial Profiling Events

SITC 2019 may be over, but the era of Spatial Genomics enabled by the GeoMx Digital Spatial Profiler has just begun.

The curtains have fallen on SITC 2019—the 34th annual meeting organized by the Society for Immunotherapy of Cancer—but excitement amongst the participants remains high after five days of knowledge exchange…

Laura Tabellini Pierre / December 10, 2019