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Oncolytic virus-driven immune modulation and therapeutic combinations: Tackling the “Cold Tumor Space”

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  • 9:00 am (PDT)
Speakers: Philipp Müller, PhD, Senior Principal Scientist, Cancer Immunology & Immune Modulation Department, Boehringer Ingelheim

Xtalks Webinar Presentation

This webinar will provide a short introduction to immuno-oncology, the shortcomings of current standard of care checkpoint inhibitors and the mechanism of action of oncolytic virotherapies.  We will discuss selective replication of the oncolytic virus VSV-GP in tumor cells, tumor cell lysis and reshaping of the tumor microenvironment. The results from this study explore the potential of VSV-GP as an immuno-oncology enabler for a broad range of cancers in poorly “T-cell inflamed” tumors and highlight VSV-GP as a non-mutagenic virus that synergizes with other immunotherapies as well as targeted therapies.

FOR RESEARCH USE ONLY. Not for use in diagnostic procedures.