Masthead

AMP Virtual Corporate Workshop

Masthead

Association for Molecular Pathology

Wednesday, Nov. 17, 2021

1:30 – 2:20 PM ET

*Virtual Format

Workshop Description

Nanostring GeoMx Panels: Strategies for Clinical Validation

The development of new biomarker panels for the Nanostring GeoMx® Digital Spatial Profiler offers new opportunities to explore biological heterogeneity present in biopsies of advanced solid tumors. GeoMx panels enable highly multiplexed quantification of protein and phospho-protein targets relevant to the selection of cancer therapeutics, including intracellular signaling and immune biomarkers. We have developed standard controls that assess antibody performance and support inter-run and inter-laboratory data normalization. The approach uses FFPE cancer cell lines, some of them treated with drugs or growth factors, arranged in a tissue microarray. These controls are being used in an ongoing collaboration between our laboratories and Mayo Clinic Laboratories to evaluate the GeoMx® Digital Spatial Profiler for use in routine clinical testing. 

NanoString Corporate Workshop

Virtual Format

Date: Wednesday, Nov. 17 | 1:30 pm ET

Developing spatial biomarker assays for clinical validation using GeoMx® Digital Spatial Profiler

Speakers:

Introduction by:

Nicholas Confuorto, Senior Director, DSP Business Unit, NanoString Technologies

Presentation by:

Christopher Corless, MD, PhD, Director, Knight Diagnostic Laboratories, Oregon Health & Science University, Portland, Oregon