nCounter® MAX Analysis System
For Core Facilities
Expandable throughput to analyze differential expression of genes and proteins.
Options For Growth: NanoString provides the option to grow into the MAX configuration. Start with one Prep Station and one Digital Analyzer. Add a second Prep Station when needed and double your capacity to match a growing number of users.
Maximize Throughput: Two nCounter® Prep Stations and a separate Digital Analyzer help eliminate bottlenecks in sample processing and data collection. Process 96 lanes per day and up to 384 samples with additional sample plexing.
Secure Access: An enterprise software package is included for laboratories that require enhanced security. Control user access, automate data flow, and generate audit logs.
Unattended Data Collection: The Digital Analyzer can load up to six cartridges at a time for unattended scanning overnight. Random access enables users to pause data collection to load or remove additional cartridges without waiting for the run to finish.
nCounter® MAX Analysis System Specifications
- Supported Applications
- Compatible Chemistries
|RNA:Protein||Perform multianalyte measurement of both RNA and proteins simultaneously.|
|mRNA||Automated RNA profiling without cDNA synthesis, library prep, or amplification.|
|miRNA||Specific measurements of microRNA transcriptomes from human, mouse, and rat.|
|CNV||Highly accurate and reproducible detection of gene copy number variation.|
|Fusion Genes||Find breakpoint locations and specific junction sequences.|
Compatible Barcode Chemistries
|For Pathway Analysis||For Lab Tests|
|nCounter CodeSets||nCounter Elements|
|Targets per sample||20 - 800||216|
|Samples per Lane||Up to 4||1|
|Total samples per run||Up to 48||12|
*Assay comes with gene-specific probes and/or epitope-specific antibodies.
Core Consumables: nCounter Master Kit
Contains all necessary reagents. Requires sample and nCounter CodeSet. Learn more about the Master Kit Contents.
Platform Performance Specifications
|Multiplexing capacity||Up to 800 targets|
|Recommended amount of starting material||RNA:
- 50 ng (using high sensitivity protocol)
- 300 ng
- 400-5,000 cell equivalent lysates
|Supported sample types||Total RNA, cell lysates in GITC, FFPE-derived total RNA, and PAXgene-lysed whole blood|
|Reaction volume||Up to 30 μL|
|Detection limit||15 zeptomole spike-in control|
|Fold change sensitivity||> 1.5-fold (if > 5 copies per cell)
> 2-fold change (if > 1 copy per cell)
|Spike correlation||R² ≥ 0.95|
|Linear dynamic range||7 x 10⁵ total counts|
|Prep Station throughput*||12 samples per 2.5 hours|
|Digital Analyzer throughput*||12 samples per 2.7 hours|
*Optional settings may require less processing time with reduced sensitivity.
|2 Prep Stations||Digital Analyzer|
|Humidity||20 - 80% (non-condensing)||20 - 80% (non-condensing)|
|Power source||100-240 VAC, 50-60 Hz||100-240 VAC, 50-60 Hz|
|Power draw||610 VA||610 VA|
|Dimensions||67 x 89 x 63 cm||66 x 66 x 48 cm|