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nCounter Max
nCounter MAX
















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nCounter® MAX Analysis System

For Core Facilities

Expandable throughput to analyze differential expression of genes and proteins.

Options For Growth: NanoString provides the option to grow into the MAX configuration. Start with one Prep Station and one Digital Analyzer. Add a second Prep Station when needed and double your capacity to match a growing number of users.

Maximize Throughput: Two nCounter® Prep Stations and a separate Digital Analyzer help eliminate bottlenecks in sample processing and data collection. Process 96 lanes per day and up to 384 samples with additional sample plexing.

Secure Access: An enterprise software package is included for laboratories that require enhanced security. Control user access, automate data flow, and generate audit logs.

Unattended Data Collection: The Digital Analyzer can load up to six cartridges at a time for unattended scanning overnight. Random access enables users to pause data collection to load or remove additional cartridges without waiting for the run to finish.

nCounter® MAX Analysis System Specifications

  • Supported Applications
  • Compatible Chemistries
  • Software
  • Specifications

Supported Applications

Application Description
RNA:Protein Perform multianalyte measurement of both RNA and proteins simultaneously.
mRNA Automated RNA profiling without cDNA synthesis, library prep, or amplification.
miRNA Specific measurements of microRNA transcriptomes from human, mouse, and rat.
CNV Highly accurate and reproducible detection of gene copy number variation.
Fusion Genes Find breakpoint locations and specific junction sequences.

Compatible Barcode Chemistries

For Pathway Analysis For Lab Tests
nCounter CodeSets nCounter Elements
Pre-configured panels* + -
Custom assays + -
Targets per sample 20 - 800 216
Samples per Lane Up to 4 1
Total samples per run Up to 48 12

*Assay comes with gene-specific probes and/or epitope-specific antibodies.

Core Consumables: nCounter Master Kit

nCounter Master Kit

Contains all necessary reagents. Requires sample and nCounter CodeSet. Learn more about the Master Kit Contents.

Included Software

For Design For Analysis
nDesign™ Gateway nSolver™ Analysis Software
Create custom CodeSets. Automated QC, normalization, and analysis of nCounter data.

Platform Performance Specifications

Description Specification
Multiplexing capacity Up to 800 targets
Recommended amount of starting material RNA:
- 50 ng (using high sensitivity protocol)
DNA:
- 300 ng
RNA:Protein:
- 400-5,000 cell equivalent lysates
Supported sample types Total RNA, cell lysates in GITC, FFPE-derived total RNA, and PAXgene-lysed whole blood
Reaction volume Up to 30 μL
Detection limit 15 zeptomole spike-in control
Fold change sensitivity > 1.5-fold (if > 5 copies per cell)
> 2-fold change (if > 1 copy per cell)
Spike correlation R² ≥ 0.95
Linear dynamic range 7 x 10⁵ total counts
Prep Station throughput* 12 samples per 2.5 hours
Digital Analyzer throughput* 12 samples per 2.7 hours
Controls Assay-dependent

*Optional settings may require less processing time with reduced sensitivity.

Hardware Specifications

2 Prep Stations Digital Analyzer
Prep Station Digital Analyzer
Operating Temperature 18-28°C 18-28°C
Humidity 20 - 80% (non-condensing) 20 - 80% (non-condensing)
Pollution degree 2 2
Power source 100-240 VAC, 50-60 Hz 100-240 VAC, 50-60 Hz
Power draw 610 VA 610 VA
Dimensions 67 x 89 x 63 cm 66 x 66 x 48 cm

Request Information | E-mail us: info@nanostring.com | Call us: 1 888 358 6266