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nCounter Vantage™ Lung Fusion Panel

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The nCounter® Lung Fusion Panel includes 63 probes: 35 for specific fusion detection, 24 for positional gene expression imbalance detection, and 4 internal reference genes.

Specific Lung Gene Fusion Probes detect the following gene fusion families:

ALK RET ROS NTRK1
EML4-ALK CCDC6-RET CD74-ROS1 CD74-NTRK1
HIP1-ALK KIF5B-RET EZR-ROS1 MPRIP-NTRK1
KIF5B-ALK   GOPC-ROS1  
TFG-ALK   LRIG3-ROS1  
TPR-ALK   SDC4-ROS1  
    SLC34A2-ROS1  
    TPM3-ROS1  

Lung Imbalance probes detect gene expression imbalance in the following genes:

ALK RET ROS
8 probes 8 probes 8 probes
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