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Simplified Workflow Streamlines Validation of Copy Number Variations
Copy Number Variations (CNVs) have become recognized as a prevalent form of structural variation in the genome contributing to genetic variability and are a growing area of interest in clinical research.
Discovery technologies for detecting CNVs, however, can be subject to considerable false-positive rates. As a result, detected variants of interest are generally validated by real-time quantitative PCR (qPCR). This technique is labor intensive and not readily scalable for validating or screening many genomic regions at once, creating a bottleneck in the CNV analysis workflow.
The nCounter Custom Copy Number Variation Assays are expected to eliminate this bottleneck by enabling researchers to perform highly multiplexed, direct digital detection and counting of CNVs in a single reaction without technical replicates.
NanoString is currently accepting applications for early access use of the Custom CNV Assays. To inquire about becoming an early access customer, please contact an account representative.
Want to be among the first to know when the new CNV Assays become available? Join the nCounter community today.